tablet dissolution tester


Salient Features

  • Complies with USP, IP, BP, DAB specifications
  • Ergonomically designed control panel with membrane keyboard
  • Sturdy bath top plate with precise vessel centering facility
  • Automated sampling with Peristaltic Pump, Fraction Collector and Manifold
  • Validation printout of test parameters
  • Supports USP apparatus 1, 2, 5 and 6
  • 12 programmable mono- graphs and sampling intervals
  • Ideal for sustained and controlled release products
  • Supports both glass and Merlon jars
  • Easy and secure installation

Dissolution testing is one of the most important tests carried out by the pharmaceutical industry on solid dosage forms like tablets, capsules and pellets.

Our tablet dissolution tester automates this accurate and precise task used for Quality Control and R&D of pharmaceuticals in its stand alone model.
This microprocessor based tester anticipates and even exceeds USP requirements. Performance, reliability, accuracy and operator ergonomics - the tester simply defies comparison.

Integrating this unit with the peristaltic pump and fraction collector automates the task of sampling. This model validates on-line system performance with a printer link.

The tester with 6 stirring stations is user friendly since it eliminates numerous routine manual operations. The position of the 6 test vessels plus replenishment vessel are designed for easy accessibility. The moulded merlon jars are perfectly cylindrical at the top and the bottom portion is a precise hemisphere with three self - supporting legs.

The critical positioning of the stirrers in all six test vessels and the precise distance from the bottom is achieved automatically. A comprehensive self -check routine which is initiated when power is switched on gives reliable self-diagnostics: Modular construction includes plug-in PCB's making serviceability and field upgrading an easy task.

Twelve programmable sampling intervals and RPM's can be set. The microprocessor precisely controls and displays the RPM using a built-in tachometer. An auto- calibration system ensures a reliable and accurate control of temperature. The test will not start until the set temperature is achieved. An external probe is provided to monitor and validate bath or individual test vessel temperature. An audible beep is given at the end of each sampling interval.

The RUN, HALT, READY and TEMP ON LED indicators reflect the status of the instrument.

Twelve individual mono- graphs can be set, stored and recalled for each test sequence. These parameters are retained by a battery backed up RAM.

Assured System Performance
A print interval from 1 to 60 minutes can be set and a documented validation report of all critical operating parameters including percentage deviation in RPM and difference in test temperatures is printed during the test. Thus the system performance is assured even when the instrument is unattended.

Fraction Collector
The Fraction Collector can collect a set of 12 samples. which are arranged in a 6 X 12 matrix in a removable tray. A maxi- mum volume of upto 50 ml per sample can be collected.

Standard Accessories -7 merlon jars with lids, 6 paddles, 6 baskets, 6 basket shafts, stirrer paddle, clear acrylic water bath, external probe, polyester coated bath top plate.

Optional Accessories -Coloured acrylic-water bath, P. T.F.E. coated paddles, gold plated baskets, sinker for capsule as per JAPAN XI, transdermal disk, 8. 8. cylinder stirring element, 8.8. sintered filter, sampling manifold, 250 ml and 21iters glass jars with their respective accessories, sampler pump, pump cassette set, tube set, 8.8. tube set, fraction collector, sampling bottles (20/50 ml) 72 nos., printer (80 column).

Technical Specifications
Parameter Range Accuracy Resolution
RPM 25 -200 ± 1 1
Temperature
30.0°C to 40.0°C
± 0.2°C 0.1°C
Internal Range
1 min to 99 hrs 59 min
± 0.1 % 1 min
No. of Intervals
12
Volume Range
1 - 90 ml
Bath
W 600 x D 300 X H 225 made of 8 mm thick acrylic
Heater
1 KW S.S. with RTD sensor
Printer Interface
Centronics parallel port
Power
220 / 230 V, 50 Hz, 1.2 Kw
100 / 110 V, 50 Hz (on request)
Weight
Net 90 kgs Gross 160 kgs

   
3F4 Shankardham, Sundervan Complex, Off Lokhandwala Complex Road, Andheri W, Mumbai 400053
Tel: +91 22 26313092 / 26314574 / 26314079 • Fax: +91 22 26313014 • Email: office@groversequip.com